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Reference Standards

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MetaGene Pty Ltd, Reference Standards, Horizon

Reference Material Formats

Horizon provides a wide range of reference material formats to address the needs of almost any assay.

Explore the reference standards by format:

 

Genomic DNA

Reference Standards, MetaGene Pty Ltd

 


Validated allelic frequency using digital PCR

 

• Precisely validated allelic frequency [50%]
• Allelic frequency can be diluted as required
• Highly consistent renewable resource
• Independent assay validation and routine monitoring of analytical performance for both specificity and sensitivity

 

Genomic DNA

FFPE Sections

 


Consistent allelic frequency throughout FFPE block

 

• Range of precisely validated allelic frequencies [1%-50%]
• Standards mimic cancer patient genetics and processed tissue sample quality
• Test the integrity of a molecular assay workflow [extraction, quantification, molecular testing and data analysis]

 

FFPE Sections

Formalin-Compromised DNA

Reference Standards, MetaGene Pty Ltd

 


Fragmentation profiled by Tapestation Assay

 

• Range of precisely validated allelic frequencies [1-25%]
• Standards mimic the impact of formalin
• DNA format extracted from formalin-treated cells to be placed straight into the assay

 

fcDNA

Genome in a Bottle FFPE Sections

Reference Standards, MetaGene Pty Ltd

 


Highly Characterized FFPE Reference Standards for your NGS Workflow

 

• Compare your data with the community as part of the Personal Genome Project (PGP)
• Coverage of over 99.5% of genes with clinical testing available

 

Genome In A Bottle

Cell Free DNA (cfDNA)

Reference Standards, MetaGene Pty Ltd

 

 

Reference standard to aid the assessment and validation of cfDNA assays

 

• Available as fragmented cell line DNA to an average size of 160bp
• Allelic frequency and gene copy number validated with ddPCR
• Multiplex and Singleplex versions available

 

Cell-free DNA

We also offer a Fast-track Custom Reference Standards option, allowing you to pick pre-existing variants into new formats.

To find out more about Horizon products click here.

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