BLADDER
Amplification at the 5p152.2 locus is strongly linked to high-grade, advanced-stage bladder tumors and rapid tumor cell proliferation in urinary cancer. Cytogenic analysis is demonstrated that 5p might be involved in translocations and/or formation of isochromosomes in a substancial number of bladder tumors. Gains at Chromosomes 3, 7, and 10 are seen more frequently in urothelial tumors.