Santa Cruz Biotechnology

Validated, Certified & Low Cost Pathology, Histology & Cancer Research Products, MetaGene Pty Ltd, Santa Cruz Biotechnology
Santa Cruz Biotechnology, Metagene Pty Ltd

Monoclonal Antibodies

As the leading source for primary antibodies and support reagents, Santa Cruz Biotechnology offers over 21,000 monoclonal antibodies directed to a broad range of mammalian and non-mammalian protein targets.

Santa Cruz Biotechnology, Metagene Pty Ltd

Santa Cruz Biotechnology is the #1 supplier of biochemicals for research. Santa Cruz Biotechnology now offers over 175,000 specialty biochemicals under the ChemCruz® brand. Their Protein-Interacting Inhibitors, Activators and Substrates are designed to work seamlessly with their primary antibodies to study protein function. More generalised chemicals such as Prepared Buffers, Detergents and Solvents are suitable for everyday laboratory use. In-stock products are available for immediate, overnight shipping. They also offer Custom Synthesis and Special Order services.


Santa Cruz Biotechnology now offers a broad range of convenient Prepared Buffers. The prepared buffers are formulated based on standard protocols, feature high-quality raw materials, and may be used in various immunoassays, including immunofluorescence, IHC, ELISA, and WB. Their popular PBS, TBS, and TBST buffers are offered in ready to use packets of the premixed ingredients, or in pre-filtered liquid formats. High quality acrylamides, APS, and TEMED are available for gel preparation. Proprietary formulas are also available, such as their Western Blot Stripping buffer which conserves loading proteins by allowing you to reprobe your gel multiple times with different antibodies.

Stains, Dyes and Probes

High quality Stains, Dyes and Fluorescent Probes are available for use in various immunoassays including Flow Cytometry, Immunofluorescense, ImmunoHistoChemistry, and other applications.

Santa Cruz Biotechnology, Metagene Pty Ltd

siRNA & shRNA

Santa Cruz Biotechnology now offers siRNA and shRNA (plasmid and lentiviral) gene silencers targeted to all (100%) known human and mouse genes. siRNAs are provided as pools of 3 target specific 19-25 nt siRNAs designed to knock down expression of specific gene of interest. Each vial contains 3.3 nmol of lyophilized siRNA and is sufficient for 50-100 transfections. For independent verification of gene silencing results, they also provide, upon request, individual siRNA duplex components, each containing 3.3 nmol of lyophilized siRNA.

CRISPR/CAS 9 Knockout & Double Nickase Plasmids

Santa Cruz Biotechnology now offers target-specific CRISPR/Cas9 Knockout (KO) Plasmids, CRISPR Double Nickase Plasmids, CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for over 18,910 human and 18,340 mouse protein encoding genes. CRISPR/Cas9 KO Plasmids and CRISPR Double Nickase Plasmids enable the identification and cleavage of specific genes encoding a protein of interest thereby eliminating production of that gene product (protein). CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems activate endogenous gene transcription using a robust synergistic activation mediator (SAM) system. This exciting new technology is a useful tool for studying protein function and signaling pathways.

Santa Cruz Biotechnology is a world leader in the development of products for the biomedical research market. Over the past twenty years, the company has focused on the ongoing development of research monoclonal antibodies, biochemicals, labware and CRISPR products. Santa Cruz Biotechnology has the highest commitment to quality and customer service.

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