Fermenters and Bioreactors

Metagene Pty Ltd, Fermenters, Bioreactors

IO is a mini fermenter/bioreactor suitable for beginners and experienced users alike.

With total volumes 200mL and 1000mL and two different ratio H/D represents a great innovative device for process development. P

CS is managing up to 24 units with parallel control.

• Up to 24 units managed with one HMI with innovative PARALLEL process control LEONARDO: smart controller designed to provide an high level of automated management of the fermentation/cultivation processes
• Batch, Fed batch or continuous processes
• Different gas mixing strategies with up to 5 TMFC
• 23’’ (single unit) or 27’’ (multi system) multi touch HMI
• Remote control via PC, tablet and smartphone for process management and after sale assistance
• Powerful/ Accurate brushless motor, from 1 to 2000 RPM. Online absorbed Torques (Nm) and Power (W) measurements obtaining an indirect density indication of the culture broth.
• Modbus Digital Hamilton sensors
• LEDA safe sterile sampling system. The needle free connector is designed to reduce the risk of contamination during sampling. The sterile combination of a syringe (3-5-10-30mL) and a non return valve guarantees the sterility after sampling until the next use.
• Compact and modular PCS (350 x 350 x 350mm). Additional parameter in modular external boxes for future PCS upgrade Including dCO², cell density, weight, peristaltic pumps, etc.
• N.4 assignable Watson Marlow pumps, all speed controlled in entry level
• No water circulation – thermoregulation performed through Peltier cell

Metagene Pty Ltd, Fermenters, Bioreactors

The peculiarity that makes unique fermentation processes is the difficulty and complexity of scale-up.

Successful scale-up means a shortened cycle to full-scale production, competitive advantage, and cost savings.

Currently bench top autoclavable R&D fermenters on the market are largely if not exclusively working at non controlled atmospheric pressure. That represent a substantial limitation in terms of Oxygen Transfer for R&D and particularly for future scale up. Solaris has filled the gap with the launch of VENUS.

• Up to 24 units managed with one HMI with innovative PARALLEL process control LEONARDO: smart controller designed to provide an high level of automated management of the fermentation/cultivation processes
• Batch, Fed batch or continuous processes
• Different gas mixing strategies with up to 5 TMFC
• 23’’ (single unit) or 27’’ (multi system) multi touch HMI
• Remote control via PC, tablet and smartphone for process management and after sale assistance
• Powerful/ Accurate brushless motor, from 1 to 2000 RPM. Online absorbed Torques (Nm) and Power (W) measurements obtaining an indirect density indication of the culture broth
• Modbus Digital Hamilton sensors
• Compact and modular PCS (350 x 350 x 350mm)
• N.4 assignable Watson Marlow pumps, all speed controlled in entry level
• Fully removable and cleanable glass jacket for an improved heat transfer during autoclaving.

ELARA FLAT

Photobioreactors

ELARA Flat photobioreactors is ideal for phototrophic organisms as moss, microalgae, bacteria and plant cells under optimum conditions. The light intensity is dimmable from 0-100% up to 3000 μmol(photon)/m². Luminostat mode via radiation sensor.

• Up to 24 units managed with one HMI with innovative PARALLEL process control LEONARDO: smart controller designed to provide an high level of automated management of the fermentation/cultivation processes.
• 23’’ (single unit) or 27’’ (multi system) multi touch HMI
• Remote control via PC, tablet and smartphone for process management and after sale assistance
• Assymetric shape to prevent foam formation
• Homogeneous light distribution
• Automatic and manual control of light intensity and circadian cycle simulation
• Modbus Digital Hamilton sensors
• LEDA safe sterile sampling system
• Safety: pressure releaf valve included in each unit
• Compact and modular PCS (350 x 350 x 350mm)
• N.4 assignable Watson Marlow pumps, all speed controlled in entry level
• Additional External modular box: OD, dCO2, weight, thermobox, peristaltic pumps
• Parts in contact with the culture made in borosilicate glass and Super duplex SAF 2507 highly resistant to salty water
• Airlift mixing process Different gas mixing strategies with

Metagene Pty Ltd, Fermenters, Bioreactors, Solaris Biotech

HOMOGENEOUS LIGHT DISTRIBUTION
The flat design with the minimum thickness allows an homogenueous light distribution even at high viscosity.

AIRLIFT
Gentle mix performed through the air lift prevents the damages at the cell membrane ensuring an efficient homogenisation.

ASYMMETRICAL SHAPE
Facing the foam formation problem the asymmetrical shape is your best ally.

MATERIALS
Parts in contact with the culture made in borosilicate glass and Super duplex SAF 2507 give high resistant to salty water.

Metagene Pty Ltd, Fermenters, Bioreactors

M series are standard SIP Fermenters/Bioreactors available in a range of six different volumes volumes from 30 up to 200 litres with a wide range of options and accessories.

• TK connection rather than TC ensures a better cleanibility and easier sterilisation
• Pneumatic cover lift
• Re-sterilisable addition system (steam bridge)
• Multiple sensors options pH, dO², Redox, Total Cell density, Viable Cell density, Conductivity, dCO²
Double jacket (side/bottom). Increased heat transfer efficiency. It ensures optimal temperature control and sterilisation even at minimum volumes.
• Top or bottom Powerful/Accurate brushless motor, from 1 to 2000 RPM. Online absorbed Torques (Nm) and Power (W) measurements obtaining an indirect density indication of the culture broth.
• Tri-Clamp stainless steel piping
• Obtaining an indirect density indication of the culture broth
• Different gas mixing strategies with up to 5 TMFC
• Automatic mechanical seal lubrication with steam condensate loop
• 19’’ coloured touch screen industrial HMI SBC16: smart controller designed to provide an high level of automated management of the fermentation/cultivation processes. Customisable PID or factory default
• N.4 Watson Marlow speed controlled valves. Pumps totaliser integrated in the software
• N.2 heat exchangers and recirculating pump
• Separate drains, cooling return,condense to waste,hot condense return
• Compact design

To find out more about Solaris Biotech products click here.

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